Manchester United moved into the League Cup fourth round with a 3-0 win at Luton, while West Ham boss David Moyes and two of his players contracted the coronavirus ahead of their 5-1 victory against Hull as the pandemic caused chaos on Tuesday.

Moyes, Josh Cullen and Issa Diop all left the London Stadium after learning of the tests before kick-off and will self-isolate, with the trio said to be asymptomatic.

West Ham were not the only Premier League club affected by the virus as Tottenham’s tie at Leyton Orient was postponed after their fourth tier opponents suffered a Covid-19 outbreak.

West Ham’s match went ahead as planned despite the virus tests, with assistant manager Alan Irvine taking charge of the Hammers.

“At 20 past six we suddenly got some information from our doctor and head physio to say there were three positive tests, the manager and the two players,” Irvine said.

“We’d had contact insofar as we were in the same area of the stadium as David.

“We were shocked by the news. We’ve had so many tests and not had any positive. But we’ve been very particular about protocol right from the start.”

Sebastien Haller and Andriy Yarmolenko both struck twice for West Ham after Robert Snodgrass opened the scoring.

West Bromwich Albion crashed out against second tier Brentford, losing 5-4 on penalties after a 1-1 draw at the Hawthorns.

Grady Diangana was the only Albion player to miss in the shoot-out and Christian Norgaard netted Brentford’s winner to earn a tie against Fulham or Sheffield Wednesday.

Newport reached the competition’s last 16 for the first time in their history as the fourth tier side beat Championship club Watford 3-1